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sieves used in pharmaceuticals - An Overview
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SEC performs also in a preparative way by trapping the lesser molecules within the pores of the particles. The larger sized molecules only pass by the pores as They can be too massive to enter the pores. More substantial molecules hence circulation from the column quicker than scaled-down molecules: that is certainly, the more compact the molecule,
About hplc column types
The sensible drawbacks stem with the excessive strain fall needed to power cell fluid through the column and The problem of making ready a uniform packing of incredibly high-quality materials.[24] Each and every time particle size is minimized substantially, A further round of instrument advancement commonly must happen to deal with the strain.[twe